115 citations · 912 across the 37 of their papers we have counts for
5 papers · 1 filter
A biologically motivated three-species exclusion model: effects of leaky scanning and overlapping genes on initiation of protein synthesis
Bhavya Mishra, Debashish Chowdhury
Totally asymmetric simple exclusion process (TASEP) was originally introduced as a model for the traffic-like collective movement of ribosomes on a messenger RNA (mRNA) that serves…
First-passage processes on a filamentous track in a dense traffic: optimizing diffusive search for a target in crowding conditions
Soumendu Ghosh, Bhavya Mishra, Anatoly B. Kolomeisky +1
Several important biological processes are initiated by the binding of a protein to a specific site on the DNA. The strategy adopted by a protein, called transcription factor (TF),…
A Biologically Motivated Asymmetric Exclusion Process: interplay of congestion in RNA polymerase traffic and slippage of nascent transcript
Soumendu Ghosh, Annwesha Dutta, Shubhadeep Patra +3
We develope a theoretical framework, based on exclusion process, that is motivated by a biological phenomenon called transcript slippage (TS). In this model a discrete lattice repr…
A pattern in the imaging data: mere artefact of spatio-temporal resolution
Swayamshree Patra, Swagata Dey, Krishanu Ray +1
{\it ' Seeing is believing '} \cite{north06}- is the fundamental philosophy of optical imaging based on light microscopy \cite{ntziachristos10}. Since the pioneering works of Anton…
Fidelity of bacterial translation initiation: a stochastic kinetic model
Dipanwita Ghanti, Kelvin Caban, Joachim Frank +2
During the initiation stage of protein synthesis, a ribosomal initiation complex (IC) is assembled on a messenger RNA (mRNA) template. In bacteria, the speed and accuracy of this a…