2 papers
stat.ME2026
Tools to help patients and other stakeholders' input into choice of estimand and intercurrent event strategy in randomised trials
Joanna Hindley, Charlotte Hartley, Jennifer Hellier +10
Estimands can help to clarify the research questions being addressed in randomised trials. Because the choice of estimand can affect how relevant trial results are to patients and…
stat.ME2025
When do composite estimands answer non-causal questions?
Brennan C Kahan, Tra My Pham, Conor Tweed +1
Under a composite estimand strategy, the occurrence of the intercurrent event is incorporated into the endpoint definition, for instance by assigning a poor outcome value to patien…