2 papers
stat.ME2026
A response-adaptive multi-arm design for continuous endpoints based on a weighted information measure
Gianmarco Caruso, Pavel Mozgunov
Multi-arm trials are gaining interest in practice given the statistical and logistical advantages they can offer. The standard approach uses a fixed allocation ratio, but there is…
stat.ME2025
Informed Burn-In Decisions in RAR: Harmonizing Adaptivity and Inferential Precision Based on Study Setting
Lukas Pin, Stef Baas, Gianmarco Caruso +2
Response-Adaptive Randomization (RAR) is recognized for its potential to deliver improvements in patient benefit. However, the utility of RAR is contingent on regularization method…