3 papers
q-bio.GN2026
GP-DHT: A Dual-Head Transformer with Contras-tive Learning for Predicting Gene Regulatory Rela-tionships across Species from Single-Cell Data
Shuai Yan, Qingzhi Yu, Wengfeng Dai +1
Gene regulatory networks (GRNs) are essential for understanding cell fate decisions and disease mechanisms, yet cross-species GRN inference from single-cell RNA-seq data remains ch…
q-bio.QM2025
Heterogeneous network drug-target interaction prediction model based on graph wavelet transform and multi-level contrastive learning
Wenfeng Dai, Yanhong Wang, Shuai Yan +2
Drug-target interaction (DTI) prediction is a core task in drug development and precision medicine in the biomedical field. However, traditional machine learning methods generally…
cs.LG2025
HyboWaveNet: Hyperbolic Graph Neural Networks with Multi-Scale Wavelet Transform for Protein-Protein Interaction Prediction
Qingzhi Yu, Shuai Yan, Wenfeng Dai +1
Protein-protein interactions (PPIs) are fundamental for deciphering cellular functions,disease pathways,and drug discovery.Although existing neural networks and machine learning me…