4 papers
Principles of Client Enrichment in Multicomponent Biomolecular Condensates
Aishani Ghosal, Nicholas E. Lea, Lindsay B. Case +1
Biomolecular condensates are commonly organized by a small number of scaffold molecules that drive phase separation together with client molecules that do not condense on their own…
Roadmap for Condensates in Cell Biology
Dilimulati Aierken, Sebastian Aland, Stefano Bo +38
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a works…
Coarse-Graining via Lumping: Exact Calculations and Fundamental Limitations
Gianluca Teza, Attilio L. Stella, Trevor GrandPre
Detecting broken time-reversibility at micro- and nanoscale is often difficult when experiments offer limited state resolution. We introduce a lumping method that builds an effecti…
Direct estimates of irreversibility from time series
Trevor GrandPre, Gianluca Teza, William Bialek
The arrow of time can be quantified through the Kullback-Leibler divergence () between the distributions of forward and reverse trajectories in a system. Many approaches to…