35 citations · 113 across the 12 of their papers we have counts for
6 papers · 1 filter
Identity and divergence of protein domain architectures after the Yeast Whole Genome Duplication event
D. Fusco, L. Grassi, A. L. Sellerio +4
Analyzing the properties of duplicate genes during evolution is useful to understand the development of new cell functions. The yeast S. cerevisiae is a useful testing ground for t…
DrosOCB: a high resolution map of conserved non coding sequences in Drosophila
L. Martignetti, M. Caselle, B. Jacq +1
Comparative genomics methods are widely used to aid the functional annotation of non coding DNA regions. However, aligning non coding sequences requires new algorithms and strategi…
Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions
Davide Cora, Ferdinando Di Cunto, Michele Caselle +1
3' untranslated regions (3' UTRs) contain binding sites for many regulatory elements, and in particular for microRNAs (miRNAs). The importance of miRNA-mediated post-transcriptiona…
Universal power law behaviors in genomic sequences and evolutionary models
L. Martignetti, M. Caselle
We study the length distribution of a particular class of DNA sequences known as 5'UTR exons. These exons belong to the messanger RNA of protein coding genes, but they are not codi…
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis
A. Re, D. Cora, A. M. Puliti +2
Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several investigation…
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Davide Cora', Carl Herrmann, Christoph Dieterich +3
We discuss a simple and powerful approach for the ab initio identification of cis-regulatory motifs involved in transcriptional regulation. The method we present integrates several…