342 citations · 1.2k across the 38 of their papers we have counts for
8 papers · 1 filter
Why is the condensed phase of DNA preferred at higher temperature? DNA compaction in the presence of a multivalent cation
Takuya Saito, Takafumi Iwaki, Kenichi Yoshikawa
Upon the addition of multivalent cations, a giant DNA chain exhibits a large discrete transition from an elongated coil into a folded compact state. We performed single-chain obser…
Different pathways in mechanical unfolding/folding cycle of a single semiflexible polymer
Natsuhiko Yoshinaga, Kenichi Yoshikawa, Takao Ohta
Kinetics of conformational change of a semiflexible polymer under mechanical external field were investigated with Langevin dynamics simulations. It is found that a semiflexible po…
Entrapping a polymer chain in a light well under a good solvent condition
Masatoshi Ichikawa, Kenichi Yoshikawa, Yukiko Matsuzawa
During the last decade, the laser trapping technique has been actively applied to elucidate the property of macromolecules, DNA, RNA, cytoskeleton fibres, etc. Due to the inherent…
All-or-none switching of transcriptional activity on single DNA molecules caused by a discrete conformational transition
Ayako Yamada, Koji Kubo, Tonau Nakai +2
Recently, it has been confirmed that long duplex DNA molecules with sizes larger than several tens of kilo-base pairs (kbp), exhibit a discrete conformational transition from an el…
Phase Transition in Reconstituted Chromatin
Tonau Nakai, Kohji Hizume, Shige. H. Yoshimura +2
By observing reconstituted chromatin by fluorescence microscopy (FM) and atomic force microscopy (AFM), we found that the density of nucleosomes exhibits a bimodal profile, i.e., t…
Slowing and stopping of chemical waves in a narrowing canal
Hiroyuki Kitahata, Ryoichi Aihara, Yoshihito Mori +1
The propagation of a chemical wave in a narrow, cone-shaped glass capillary was investigated. When a chemical wave propagates from the wider end to the narrower end, it slows, stop…