4 papers
The histone octamer influences the wrapping direction of DNA on it: Brownian dynamics simulation of the nucleosome chirality
Wei Li, Shuo-Xing Dou, Peng-Ye Wang
In eukaryote nucleosome, DNA wraps around a histone octamer in a left-handed way. We study the process of chirality formation of nucleosome with Brownian dynamics simulation. We mo…
Model for processive movement of dynein
Ping Xie, Shuo-Xing Dou, Peng-Ye Wang
A model for the processive movement of dynein is presented based on experimental observations available. In the model, the change from strong microtubule-binding to weak binding of…
Dynamics of heterodimeric kinesins and cooperation of kinesins
Ping Xie, Shuo-Xing Dou, Peng-Ye Wang
Using the model for the processive movement of a dimeric kinesin we proposed before, we study the dynamics of a number of mutant homodimeric and heterodimeric kinesins that were co…
Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching
Wei Li, Shuo-Xing Dou, Peng-Ye Wang
Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome format…