5 papers
The histone octamer influences the wrapping direction of DNA on it: Brownian dynamics simulation of the nucleosome chirality
Wei Li, Shuo-Xing Dou, Peng-Ye Wang
In eukaryote nucleosome, DNA wraps around a histone octamer in a left-handed way. We study the process of chirality formation of nucleosome with Brownian dynamics simulation. We mo…
Study the effects of metallic ions on the combination of DNA and histones with molecular combing technique
Yu-Ying Liu, Peng-Ye Wang, Shuo-Xing Dou +3
The effects of monovalent (Na+, K+) and divalent (Mg2+, Ca2+, Mn2+) ions on the interaction between DNA and histone are studied using the molecular combing technique. Lamda-DNA mol…
Model for processive movement of dynein
Ping Xie, Shuo-Xing Dou, Peng-Ye Wang
A model for the processive movement of dynein is presented based on experimental observations available. In the model, the change from strong microtubule-binding to weak binding of…
Dynamics of heterodimeric kinesins and cooperation of kinesins
Ping Xie, Shuo-Xing Dou, Peng-Ye Wang
Using the model for the processive movement of a dimeric kinesin we proposed before, we study the dynamics of a number of mutant homodimeric and heterodimeric kinesins that were co…
Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching
Wei Li, Shuo-Xing Dou, Peng-Ye Wang
Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome format…