activity
20032019
most citedIonic effect on combing of single DNA molecules and observation of their force-induced melting by fluorescence microscopy

32 citations · 89 across the 13 of their papers we have counts for

collaborators

13 papers

q-bio.BM2019★ 1 cited

DHX36-mediated G-quadruplex unfolding is ATP-independent?

Hai-Lei Guo, Wei-Fei Chen, Stephane Rety +6

Chen et al. solved the crystal structure of bovine DHX36 bound to a DNA with a G-quadruplex (G4) and a single-stranded DNA segment. They believed that the mechanism they proposed m…

physics.bio-ph2017★ 22 cited

Angstrom-resolution single-molecule fluorescence resonance energy transfer reveals mechanisms of DNA helicases

Wenxia Lin, Jianbing Ma, Daguan Nong +8

Single-molecule FRET is widely used to study helicases by detecting distance changes between a fluorescent donor and an acceptor anchored to overhangs of a forked DNA duplex. Howev…

q-bio.BM2006

Model for unidirectional movement of axonemal and cytoplasmic dynein molecules

Ping Xie, Shuo-Xing Dou, Peng-Ye Wang

A model for the unidirectional movement of dynein is presented based on structural observations and biochemical experimental results available. In this model, the binding affinity…

q-bio.BM2005

On the Fibril Elongation Mechanism of the Prion Protein Fragment PrP106-126

Xin Zhao, Shuo-Xing Dou, Ping Xie +1

Mouse prion protein PrP106-126 is a peptide corresponding to the residues 107-127 of human prion protein. It has been shown that PrP106-126 can reproduce the main neuropathological…

q-bio.BM2005

The histone octamer influences the wrapping direction of DNA on it: Brownian dynamics simulation of the nucleosome chirality

Wei Li, Shuo-Xing Dou, Peng-Ye Wang

In eukaryote nucleosome, DNA wraps around a histone octamer in a left-handed way. We study the process of chirality formation of nucleosome with Brownian dynamics simulation. We mo…

q-bio.BM2005

Study the effects of metallic ions on the combination of DNA and histones with molecular combing technique

Yu-Ying Liu, Peng-Ye Wang, Shuo-Xing Dou +3

The effects of monovalent (Na+, K+) and divalent (Mg2+, Ca2+, Mn2+) ions on the interaction between DNA and histone are studied using the molecular combing technique. Lamda-DNA mol…