33 citations · 42 across the 6 of their papers we have counts for
6 papers
Challenging packaging limits and infectivity of phage λ
Elmar Nurmemmedov, Martin Castelnovo, Elizabeth Medina +2
The terminase motors of bacteriophages have been shown to be among the strongest active machines in the biomolecular world, being able to package several tens of kilobase pairs of…
Osmotic pressure: resisting or promoting DNA ejection from phage
Meerim Jeembaeva, Martin Castelnovo, Frida Larsson +1
Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the…
DNA ejection from bacteriophage: towards a general behavior for osmotic suppression experiments
Martin Castelnovo, Alex Evilevitch
We present in this work in vitro measurements of the force ejecting DNA from two distinct bacteriophages (T5 and lambda) using the smotic-suppression technique. Our data are analyz…
Binding effects in multivalent Gibbs-Donnan equilibrium
Martin Castelnovo, Alex Evilevitch
The classical Gibbs-Donnan equilibrium describes excess osmotic pressure associated with confined colloidal charges embedded in an electrolyte solution. In this work, we extend thi…
The effect of genome length on ejection forces in bacteriophage lambda
Paul Grayson, Alex Evilevitch, Mandar M. Inamdar +4
A variety of viruses tightly pack their genetic material into protein capsids that are barely large enough to enclose the genome. In particular, in bacteriophages, forces as high a…
Measuring the force ejecting DNA from phage
A. Evilevitch, M. Castelnovo, C. M. Knobler +1
We discuss how a balance can be established between the force acting to eject DNA from viral capsids and the force resisting its entry into a colloidal suspension which mimics the…