2 papers
cs.AI2026
Conditioned Generative Modeling of Molecular Glues: A Realistic AI Approach for Synthesizable Drug-like Molecules
Naeyma N. Islam, Thomas R. Caulfield
Alzheimer's disease (AD) is marked by the pathological accumulation of amyloid beta-42 (Abeta-42), contributing to synaptic dysfunction and neurodegeneration. While extracellular a…
q-bio.QM2025
Dynamicasome: a molecular dynamics-guided and AI-driven pathogenicity prediction catalogue for all genetic mutations
Naeyma N Islam, Mathew A Coban, Jessica M Fuller +6
Advances in genomic medicine accelerate the identi cation of mutations in disease-associated genes, but the pathogenicity of many mutations remains unknown, hindering their use in…