2 papers
q-bio.QM2026
SurfSpec: Enhancing Off-Target-Agnostic Specificity by Bounding Pocket-Ligand Geometric Mismatch
Minyeong Hwang, Yoorim Gang, Ziseok Lee +5
Lead optimization in structure-based drug design aims to improve target binding while avoiding unintended interactions with off-target pockets. However, existing affinity-driven me…
eess.AS2023
SGEM: Test-Time Adaptation for Automatic Speech Recognition via Sequential-Level Generalized Entropy Minimization
Changhun Kim, Joonhyung Park, Hajin Shim +1
Automatic speech recognition (ASR) models are frequently exposed to data distribution shifts in many real-world scenarios, leading to erroneous predictions. To tackle this issue, a…