3 papers
cs.CL2026
GENERator: A Long-Context Generative Genomic Foundation Model
Wei Wu, Qiuyi Li, Yuanyuan Zhang +15
The rapid advancement of DNA sequencing has produced vast genomic datasets, yet interpreting and engineering genomic function remain fundamental challenges. Recent large language m…
cs.LG2024
ProtCLIP: Function-Informed Protein Multi-Modal Learning
Hanjing Zhou, Mingze Yin, Wei Wu +5
Multi-modality pre-training paradigm that aligns protein sequences and biological descriptions has learned general protein representations and achieved promising performance in var…
cs.LG2024
Bridge-IF: Learning Inverse Protein Folding with Markov Bridges
Yiheng Zhu, Jialu Wu, Qiuyi Li +7
Inverse protein folding is a fundamental task in computational protein design, which aims to design protein sequences that fold into the desired backbone structures. While the deve…