11 papers
Community-Level Modeling of Gyral Folding Patterns for Robust and Anatomically Informed Individualized Brain Mapping
Minheng Chen, Tong Chen, Yan Zhuang +5
Cortical folding exhibits substantial inter-individual variability while preserving stable anatomical landmarks that enable fine-scale characterization of cortical organization. Am…
Evaluation of OpenAI o1: Opportunities and Challenges of AGI
Tianyang Zhong, Zhengliang Liu, Yi Pan +73
This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, includi…
GP-GPT: Large Language Model for Gene-Phenotype Mapping
Yanjun Lyu, Zihao Wu, Lu Zhang +11
Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits a…
Bridging Brain Connectomes and Clinical Reports for Early Alzheimer's Disease Diagnosis
Jing Zhang, Xiaowei Yu, Minheng Chen +8
Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in pract…
Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer
Xiaowei Yu, Jing Zhang, Tong Chen +8
Lewy Body Disease (LBD) is a common yet understudied form of dementia that imposes a significant burden on public health. It shares clinical similarities with Alzheimer's disease (…
GyralNet Subnetwork Partitioning via Differentiable Spectral Modularity Optimization
Yan Zhuang, Minheng Chen, Chao Cao +7
Understanding the structural and functional organization of the human brain requires a detailed examination of cortical folding patterns, among which the three-hinge gyrus (3HG) ha…