3 papers
cs.LG2026
CellForge: Agentic Design of Virtual Cell Models
Xiangru Tang, Zhuoyun Yu, Jiapeng Chen +12
Virtual cell modeling aims to predict cellular responses to diverse perturbations but faces challenges from biological complexity, multimodal data heterogeneity, and the need for i…
stat.ME2025
Debiased Estimating Equation Method for Robust and Efficient Mendelian Randomization Using a Large Number of Correlated Weak and Invalid Instruments
Ruoyu Wang, Haoyu Zhang, Xihong Lin
Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental…
stat.ME2025
The permuted score test for robust differential expression analysis
Timothy Barry, Ziang Niu, Eugene Katsevich +1
Negative binomial (NB) regression is a popular method for identifying differentially expressed genes in genomics data, such as bulk and single-cell RNA sequencing data. However, NB…