253 citations · 3k across the 163 of their papers we have counts for
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Robustness under functional constraint: The genetic network for temporal expression in Drosophila neurogenesis
Akihiko Nakajima, Takako Isshiki, Kunihiko Kaneko +1
Precise temporal coordination of gene expression is crucial for many developmental processes. One central question in developmental biology is how such coordinated expression patte…
A thermodynamic force generated by chemical gradient and adsorption reaction
Takeshi Sugawara, Kunihiko Kaneko
Biological units such as macromolecules, organelles, and cells are directed to a proper location under gradients of relevant chemicals. By considering a macroscopic element that ha…
Dynamics of Coupled Adaptive Elements : Bursting and Intermittent Oscillations Generated by Frustration in Networks
Masayo Inoue, Kunihiko Kaneko
Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain thei…
A statistical-mechanical study of evolution of robustness in noisy environment
Ayaka Sakata, Koji Hukushima, Kunihiko Kaneko
In biological systems, expression dynamics that can provide fitted phenotype patterns with respect to a specific function have evolved through mutations. This has been observed in…
Discreteness-Induced Criticality in Random Catalytic Reaction Networks
Akinori Awazu, Kunihiko Kaneko
Universal intermittent dynamics in a random catalytic reaction network, induced by smallness in the molecule number is reported. Stochastic simulations for a random catalytic react…