2 papers
stat.ME2026
Event-driven type design for clinical trials with recurrent events
Jingwen Zhang, Satoshi Hattori
It is a common practice in randomized clinical trials with the standard survival outcome to follow patients until a prespecified number of events have been observed, a type of tria…
stat.ME2026
Blinded sample size re-estimation accounting for uncertainty in mid-trial estimation
Hirotada Maeda, Satoshi Hattori, Tim Friede
For randomized controlled trials to be conclusive, it is important to set the target sample size accurately at the design stage. Comparing two normal populations, the sample size c…