3 papers
stat.AP2026
Consistency Assessment of Regional Treatment Effect for Multi-Regional Clinical Trials in the Presence of Covariate Shift
Kunhai Qing, Xinru Ren, Jin Xu +1
Multi-Regional Clinical Trials (MRCTs) play a central role in the development of new therapies by enabling the simultaneous evaluation of drug efficacy and safety across diverse gl…
stat.CO2025
BKP: An R Package for Beta Kernel Process Modeling
Jiangyan Zhao, Kunhai Qing, Jin Xu
Estimating input-dependent probability surfaces from binary, binomial, categorical, or multinomial response data is a common task in statistics and machine learning. Latent Gaussia…
stat.AP2025
Regional consistency evaluation and sample size calculation under two MRCTs
Kunhai Qing, Xinru Ren, Shuping Jiang +3
Multi-regional clinical trial (MRCT) has been common practice for drug development and global registration. The FDA guidance `Demonstrating Substantial Evidence of Effectiveness fo…