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20242026
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quant-ph2026

Quantum-Centric Geometry Optimization with Wave-Function-Based Embedding

Danil Kaliakin, Akhil Shajan, Fangchun Liang +2

The EWF-(FCI,SQD) method, a wave-function-based embedding approach combining full configuration interaction (FCI) and sample-based quantum diagonalization (SQD), is a promising new…

quant-ph2026

Quantum Computations on Fusion Blanket Molten Salts

Susanta Das, Thiago J. Pinheiro Dos Santos, Subhamoy Bhowmik +14

Molten salts such as FLiBe (2LiF--BeF) are leading blanket materials for breeding and recovering tritium in fusion reactors. Predicting tritium speciation requires accurate ele…

quant-ph2026

Protein-Ligand Free Energy Perturbation on Quantum Hardware

Zhen Li, Milana Bazayeva, Thaddeus Pellegrini +6

The use of free energy perturbation (FEP) methods to study protein-ligand complexes is one of the most important tools in structure-based drug design. Because FEP methods typically…

quant-ph2024

Towards quantum-centric simulations of extended molecules: sample-based quantum diagonalization enhanced with density matrix embedding theory

Akhil Shajan, Danil Kaliakin, Abhishek Mitra +9

Computing ground-state properties of molecules is a promising application for quantum computers operating in concert with classical high-performance computing resources. Quantum em…

quant-ph2024

Accurate quantum-centric simulations of supramolecular interactions

Danil Kaliakin, Akhil Shajan, Javier Robledo Moreno +9

We present the first quantum-centric simulations of noncovalent interactions using a supramolecular approach. We simulate the potential energy surfaces (PES) of the water and metha…