105 citations · 265 across the 26 of their papers we have counts for
8 papers · 1 filter
Topological interactions between ring polymers: Implications for chromatin loops
Manfred Bohn, Dieter W. Heermann
Chromatin looping is a major epigenetic regulatory mechanism in higher eukaryotes. Besides its role in transcriptional regulation, chromatin loops have been proposed to play a pivo…
Conformational properties of compact polymers
Manfred Bohn, Dieter W. Heermann
Monte Carlo simulations of coarse-grained polymers provide a useful tool to deepen the understanding of conformational and statistical properties of polymers both in physical as we…
The influence of the cylindrical shape of the nucleosomes and H1 defects on properties of chromatin
P. M. Diesinger, D. W. Heermann
We present a model improving the two-angle model for interphase chromatin (E2A model). This model takes into account the cylindrical shape of the histone octamers, the H1 histones…
Monte Carlo simulations reveal the straightening up of an end-grafted flexible chain with a rigid side chain
Marcel Hellmann, Matthias Weiss, Dieter W. Heermann
We have studied the conformational properties of a flexible end-grafted chain (length ) with a rigid side chain (length ) by means of Monte Carlo simulations. Depending on th…
A Random Loop Model for Long Polymers
Manfred Bohn, Dieter W. Heermann, Roel van Driel
While the structure of chromatin has been studied in great detail on length scales below 30 nm, amazingly little is known about the higher-order folding motifs of chromatin in inte…
Structure of Polymer Brushes in Cylindrical Tubes: A Molecular Dynamics Simulation
Dimitar I. Dimitrov, Andrey Milchev, Kurt Binder +1
Molecular Dynamics simulations of a coarse-grained bead-spring model of flexible macromolecules tethered with one end to the surface of a cylindrical pore are presented. Chain leng…