6 papers
A unified framework for geometry-independent operator learning in cardiac electrophysiology simulations
Bei Zhou, Cesare Corrado, Shuang Qian +9
Learning neural operators on heterogeneous and irregular geometries remains a fundamental challenge, as existing approaches typically rely on structured discretisations or explicit…
Regional heterogeneity in left atrial stiffness impacts passive deformation in a cohort of patient-specific models
Tiffany MG Baptiste, Cristobal Rodero, Charles P Sillett +13
The deformation of the left atrium (LA), or its biomechanical function, is closely linked to the health of this cardiac chamber. In atrial fibrillation (AF), atrial biomechanics ar…
TorchCor: High-Performance Cardiac Electrophysiology Simulations with the Finite Element Method on GPUs
Bei Zhou, Maximilian Balmus, Cesare Corrado +3
Cardiac electrophysiology (CEP) simulations are increasingly used for understanding cardiac arrhythmias and guiding clinical decisions. However, these simulations typically require…
Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter
Mariya Mamajiwala, Cesare Corrado, Chris Lanyon +3
Atrial fibrillation (AF) is a common cardiac arrhythmia characterised by disordered electrical activity in the atria. The standard treatment is catheter ablation, which is invasive…
Cardiac Digital Twins at Scale from MRI: Open Tools and Representative Models from ~55000 UK Biobank Participants
Devran Ugurlu, Shuang Qian, Elliot Fairweather +10
A cardiac digital twin is a virtual replica of a patient's heart for screening, diagnosis, prognosis, risk assessment, and treatment planning of cardiovascular diseases. This requi…
In Silico Trials for Sex-Specific patient Inclusion Criteria in Cardiac Resynchronization Therapy: Advancing Precision in Heart Failure Treatment
Shuang Qian, Devran Ugurlu, Elliot Fairweather +12
Cardiac resynchronization therapy (CRT) guidelines are based on clinical trials with limited female representation and inconsistent left bundle branch block (LBBB) definitions. Con…