3 papers
stat.ME2026
Doubly robust augmented weighting estimators for the analysis of externally controlled single-arm trials and unanchored indirect treatment comparisons
Harlan Campbell, Antonio Remiro-Azócar
Externally controlled single-arm trials are critical to assess treatment efficacy across therapeutic indications for which randomized controlled trials are not feasible. A closely-…
stat.ME2025
Marginal and conditional summary measures: transportability and compatibility across studies
Antonio Remiro-Azócar, David M. Phillippo, Nicky J. Welton +4
Marginal and conditional summary measures do not generally coincide, have different interpretations and correspond to different decision questions. While these aspects have primari…
stat.ME2025
Estimands and Their Implications for Evidence Synthesis for Oncology: A Simulation Study of Treatment Switching in Meta-Analysis
Rebecca K. Metcalfe, Antonio Remiro-Azócar, Quang Vuong +4
The ICH E9(R1) addendum provides guidelines on accounting for intercurrent events in clinical trials using the estimands framework. However, there has been limited attention to the…