5 papers
Uncovering spatial tissue domains and cell types in spatial omics through cross-scale profiling of cellular and genomic interactions
Rui Yan, Xiaohan Xing, Xun Wang +3
Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offe…
SurvAgent: Hierarchical CoT-Enhanced Case Banking and Dichotomy-Based Multi-Agent System for Multimodal Survival Prediction
Guolin Huang, Wenting Chen, Jiaqi Yang +5
Survival analysis is critical for cancer prognosis and treatment planning, yet existing methods lack the transparency essential for clinical adoption. While recent pathology agents…
WSI-LLaVA: A Multimodal Large Language Model for Whole Slide Image
Yuci Liang, Xinheng Lyu, Wenting Chen +8
Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole…
HySurvPred: Multimodal Hyperbolic Embedding with Angle-Aware Hierarchical Contrastive Learning and Uncertainty Constraints for Survival Prediction
Jiaqi Yang, Wenting Chen, Xiaohan Xing +5
Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) Th…
OccMamba: Semantic Occupancy Prediction with State Space Models
Heng Li, Yuenan Hou, Xiaohan Xing +3
Training deep learning models for semantic occupancy prediction is challenging due to factors such as a large number of occupancy cells, severe occlusion, limited visual cues, comp…