3 papers
q-bio.MN2026
Relating biomarkers and phenotypes using dynamical trap spaces
Samuel Pastva, Kyu Hyong Park, Jordan C. Rozum +2
Connecting the dynamics of biomolecular networks to experimentally measurable cell phenotypes remains a central challenge in systems biology. Here we introduce a model-based defini…
cs.DM2025
On the number of asynchronous attractors in AND-NOT Boolean networks
Van-Giang Trinh, Samuel Pastva, Jordan Rozum +2
Boolean Networks (BNs) describe the time evolution of binary states using logic functions on the nodes of a network. They are fundamental models for complex discrete dynamical syst…
q-bio.MN2024
An open problem: Why are motif-avoidant attractors so rare in asynchronous Boolean networks?
Samuel Pastva, Kyu Hyong Park, Ondrej Huvar +2
Asynchronous Boolean networks are a type of discrete dynamical system in which each variable can take one of two states, and a single variable state is updated in each time step ac…