266 citations · 672 across the 7 of their papers we have counts for
5 papers · 1 filter
Automated point-neuron simplification of data-driven microcircuit models
Christian Rössert, Christian Pozzorini, Giuseppe Chindemi +13
A method is presented for the reduction of morphologically detailed microcircuit models to a point-neuron representation without human intervention. The simplification occurs in a…
Quantifying topological invariants of neuronal morphologies
Lida Kanari, Paweł Dłotko, Martina Scolamiero +4
Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspe…
BluePyOpt: Leveraging open source software and cloud infrastructure to optimise model parameters in neuroscience
Werner Van Geit, Michael Gevaert, Giuseppe Chindemi +6
At many scales in neuroscience, appropriate mathematical models take the form of complex dynamical systems. Parametrising such models to conform to the multitude of available exper…
Topological analysis of the connectome of digital reconstructions of neural microcircuits
Pawe Dotko, Kathryn Hess, Ran Levi +6
A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simul…
A versatile clearing agent for multi-modal brain imaging
Irene Costantini, Jean-Pierre Ghobril, Antonino Paolo Di Giovanna +11
Extensive mapping of neuronal connections in the central nervous system requires high-throughput um-scale imaging of large volumes. In recent years, different approaches have been…