activity
20122026
most citedAnalytical Formulation and Field-Theoretic Simulation of Sequence-Specific Phase Separation of Proteinlike Heteropolymers with Short- and Long-Spatial-Range Interactions

61 citations · 289 across the 12 of their papers we have counts for

collaborators

12 papers

q-bio.BM2026

Homeostatic Noise Buffering in Biomolecular Condensates Hinges on Phase Multiplicity Modulated by Interfacial and Droplet Size Effects

Jonas Wessén, Tanmoy Pal, Suman Das +1

Specific mixing or demixing of molecular species is a characteristic feature of condensed intracellular membraneless compartments. How sequence patterns of intrinsically disordered…

q-bio.BM2024★ 23 cited

Differential Effects of Sequence-Local versus Nonlocal Charge Patterns on Phase Separation and Conformational Dimensions of Polyampholytes as Model Intrinsically Disordered Proteins

Tanmoy Pal, Jonas Wessén, Suman Das +1

Conformational properties of intrinsically disordered proteins (IDPs) are governed by a sequence-ensemble relationship. To differentiate the impact of sequence-local versus sequenc…

q-bio.BM2024★ 27 cited

Electrostatics of Salt-Dependent Reentrant Phase Behaviors Highlights Diverse Roles of ATP in Biomolecular Condensates

Yi-Hsuan Lin, Tae Hun Kim, Suman Das +6

Liquid-liquid phase separation (LLPS) involving intrinsically disordered protein regions (IDRs) is a major physical mechanism for biological membraneless compartmentalization. The…

cond-mat.stat-mech2022★ 7 cited

PT-Symmetry Breaking Transitions in Polymeric Systems

Tanmoy Pal, Ranjan Modak, Bhabani Prasad Mandal

We show that classical DNA unzipping transition which is equivalently described by quantum mechanical localization-delocalization transition in the ground state of non-Hermitian si…

q-bio.BM2022★ 61 cited

Analytical Formulation and Field-Theoretic Simulation of Sequence-Specific Phase Separation of Proteinlike Heteropolymers with Short- and Long-Spatial-Range Interactions

Jonas Wessén, Suman Das, Tanmoy Pal +1

A theory for sequence dependent liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) in the study of biomolecular condensates is formulated by extendin…

cond-mat.soft2022★ 12 cited

Field theory description of ion association in re-entrant phase separation of polyampholytes

Jonas Wessén, Tanmoy Pal, Hue Sun Chan

Phase separation of several different overall neutral polyampholyte species (with zero net charge) is studied in solution with two oppositely charged ion species that can form ion-…

q-bio.BM2022★ 33 cited

Numerical Techniques for Applications of Analytical Theories to Sequence-Dependent Phase Separations of Intrinsically Disordered Proteins

Yi-Hsuan Lin, Jonas Wessén, Tanmoy Pal +2

Biomolecular condensates, physically underpinned to a significant extent by liquid-liquid phase separation (LLPS), are now widely recognized by numerous experimental studies to be…

q-bio.BM2021★ 46 cited

A Simple Explicit-Solvent Model of Polyampholyte Phase Behaviors and its Ramifications for Dielectric Effects in Biomolecular Condensates

Jonas Wessén, Tanmoy Pal, Suman Das +2

Biomolecular condensates such as membraneless organelles, underpinned by liquid-liquid phase separation (LLPS), are important for physiological function, with electrostatics -- amo…

q-bio.BM2020★ 44 cited

Subcompartmentalization of polyampholyte species in organelle-like condensates is promoted by charge pattern mismatch and strong excluded-volume interaction

Tanmoy Pal, Jonas Wessén, Suman Das +1

Polyampholyte field theory and explicit-chain molecular dynamics models of sequence-specific phase separation of a system with two intrinsically disordered protein (IDP) species in…

cond-mat.soft2015★ 7 cited

Rigidity of Melting DNA

Tanmoy Pal, Somendra M. Bhattacharjee

The temperature dependence of DNA flexibility is studied in the presence of stretching and unzipping forces. Two classes of models are considered. In one case the origin of elastic…

cond-mat.soft2014★ 9 cited

Efimov like phase of a three stranded DNA (Efimov-DNA) and the renormalization group limit cycle

Tanmoy Pal, Poulomi Sadhukhan, Somendra M. Bhattacharjee

A three-stranded DNA with short range base pairings only is known to exhibit a classical analog of the quantum Efimov effect, viz., a three chain bound state at the two chain melti…

cond-mat.soft2012★ 20 cited

Renormalization Group Limit Cycle for Three-Stranded DNA

Tanmoy Pal, Poulomi Sadhukhan, Somendra M. Bhattacharjee

We show that there exists an Efimov-like three strand DNA bound state at the duplex melting point and it is described by a renormalization group limit cycle. A nonperturbative RG i…