activity
20122026
most citedRegistering large volume serial-section electron microscopy image sets for neural circuit reconstruction using FFT signal whitening

45 citations · 52 across the 13 of their papers we have counts for

collaborators

14 papers

cs.CV2026

MicroscopyMatching: Towards a Ready-to-use Framework for Microscopy Image Analysis in Diverse Conditions

Xiaofei Hui, Haoxuan Qu, Hossein Rahmani +3

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various bi…

cs.CV2025

Towards 1000-fold Electron Microscopy Image Compression for Connectomics via VQ-VAE with Transformer Prior

Fuming Yang, Yicong Li, Hanspeter Pfister +2

Petascale electron microscopy (EM) datasets push storage, transfer, and downstream analysis toward their current limits. We present a vector-quantized variational autoencoder-based…

cs.LG2025

Budgeted Broadcast: An Activity-Dependent Pruning Rule for Neural Network Efficiency

Yaron Meirovitch, Fuming Yang, Jeff Lichtman +1

Most pruning methods remove parameters ranked by impact on loss (e.g., magnitude or gradient). We propose Budgeted Broadcast (BB), which gives each unit a local traffic budget (the…

cs.DS2025

Sparse Graph Reconstruction and Seriation for Large-Scale Image Stacks

Fuming Yang, Yaron Meirovitch, Jeff W. Lichtman

We study recovering a 1D order from a noisy, locally sampled pairwise comparison matrix under a tight query budget. We recast the task as reconstructing a sparse, noisy line graph…

q-bio.NC2025

ZAPBench: A Benchmark for Whole-Brain Activity Prediction in Zebrafish

Jan-Matthis Lueckmann, Alexander Immer, Alex Bo-Yuan Chen +15

Data-driven benchmarks have led to significant progress in key scientific modeling domains including weather and structural biology. Here, we introduce the Zebrafish Activity Predi…

cs.CV2025

Forecasting Whole-Brain Neuronal Activity from Volumetric Video

Alexander Immer, Jan-Matthis Lueckmann, Alex Bo-Yuan Chen +14

Large-scale neuronal activity recordings with fluorescent calcium indicators are increasingly common, yielding high-resolution 2D or 3D videos. Traditional analysis pipelines reduc…

cs.CV2024

Frenet-Serret Frame-based Decomposition for Part Segmentation of 3D Curvilinear Structures

Leslie Gu, Jason Ken Adhinarta, Mikhail Bessmeltsev +7

Accurately segmenting 3D curvilinear structures in medical imaging remains challenging due to their complex geometry and the scarcity of diverse, large-scale datasets for algorithm…

cs.CV2024★ 6 cited

TriSAM: Tri-Plane SAM for zero-shot cortical blood vessel segmentation in VEM images

Jia Wan, Wanhua Li, Jason Ken Adhinarta +6

While imaging techniques at macro and mesoscales have garnered substantial attention and resources, microscale Volume Electron Microscopy (vEM) imaging, capable of revealing intric…

cs.CV2021

AxonEM Dataset: 3D Axon Instance Segmentation of Brain Cortical Regions

Donglai Wei, Kisuk Lee, Hanyu Li +13

Electron microscopy (EM) enables the reconstruction of neural circuits at the level of individual synapses, which has been transformative for scientific discoveries. However, due t…

cs.CV2016★ 45 cited

Registering large volume serial-section electron microscopy image sets for neural circuit reconstruction using FFT signal whitening

Arthur W. Wetzel, Jennifer Bakal, Markus Dittrich +3

The detailed reconstruction of neural anatomy for connectomics studies requires a combination of resolution and large three-dimensional data capture provided by serial section elec…

cond-mat.mtrl-sci2016

Efficiency of Cathodoluminescence Emission by Nitrogen-Vacancy Color Centers in Nanodiamond

Huiliang Zhang, David R. Glenn, Richard Schalek +2

Correlated electron microscopy and cathodoluminescence (CL) imaging using functionalized nanoparticles is a promising nanoscale probe of biological structure and function. Nanodiam…

cs.CV2014

Automatic Annotation of Axoplasmic Reticula in Pursuit of Connectomes

Ayushi Sinha, William Gray Roncal, Narayanan Kasthuri +8

In this paper, we present a new pipeline which automatically identifies and annotates axoplasmic reticula, which are small subcellular structures present only in axons. We run our…

cond-mat.mtrl-sci2013

Silicon-Vacancy Color Centers in Nanodiamonds: Cathodoluminescence Imaging Marker in the Near Infrared

Huiliang Zhang, Igor Aharonovich, David R. Glenn +5

We demonstrate that nanodiamonds fabricated to incorporate silicon-vacancy (Si-V) color centers provide bright, spectrally narrow, and stable cathodoluminescence (CL) in the near-i…

physics.ins-det2012★ 1 cited

Multi-color correlative light and electron microscopy using nanoparticle cathodoluminescence

David R. Glenn, Huiliang Zhang, Narayanan Kasthuri +6

Correlative light and electron microscopy promises to combine molecular specificity with nanoscale imaging resolution. However, there are substantial technical challenges including…