16 citations · 46 across the 4 of their papers we have counts for
4 papers
Stochastic Modeling and Simulation of Viral Evolution
Luiza Guimarães, Diogo Castro, Bruno Gorzoni +2
RNA viruses comprise vast populations of closely related, but highly genetically diverse, entities known as quasispecies. Understanding the mechanisms by which this extreme diversi…
Neutral and Stable Equilibria of Genetic Systems and The Hardy-Weinberg Principle: Limitations of the Chi-Square Test and Advantages of Auto-Correlation Functions of Allele Frequencies
Francisco Bosco, Diogo Castro, Marcelo R. S. Briones
Since the foundations of Population Genetics the notion of genetic equilibrium (in close analogy to Classical Mechanics) has been associated to the Hardy-Weinberg (HW) Principle an…
Virus Replication as a Phenotypic Version of Polynucleotide Evolution
Fernando Antoneli, Francisco Bosco, Diogo Castro +1
In this paper we revisit and adapt to viral evolution an approach based on the theory of branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution an…
Viral Evolution and Adaptation as a Multivariate Branching Process
Fernando Antoneli, Francisco Bosco, Diogo Castro +1
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close…