341 citations · 860 across the 36 of their papers we have counts for
4 papers · 1 filter
M3D: a kernel-based test for shape changes in methylation profiles
Tom Mayo, Gabriele Schweikert, Guido Sanguinetti
DNA methylation is an intensely studied epigenetic mark implicated in many biological processes of direct clinical relevance. While sequencing based technologies are increasingly a…
The complex chemical Langevin equation
David Schnoerr, Guido Sanguinetti, Ramon Grima
The chemical Langevin equation (CLE) is a popular simulation method to probe the stochastic dynamics of chemical systems. The CLE's main disadvantage is its break down in finite ti…
Validity conditions for moment closure approximations in stochastic chemical kinetics
David Schnoerr, Guido Sanguinetti, Ramon Grima
Approximations based on moment-closure (MA) are commonly used to obtain estimates of the mean molecule numbers and of the variance of fluctuations in the number of molecules of che…
Smoothed Model Checking for Uncertain Continuous Time Markov Chains
Luca Bortolussi, Dimitrios Milios, Guido Sanguinetti
We consider the problem of computing the satisfaction probability of a formula for stochastic models with parametric uncertainty. We show that this satisfaction probability is a sm…