2 papers
q-bio.GN2013
Causes and Consequences of genetic background effects illuminated by integrative genomic analysis
Christopher H. Chandler, Sudarshan Chari, David Tack +1
The phenotypic consequences of individual mutations are modulated by the wild type genetic background in which they occur.Although such background dependence is widely observed, we…
q-bio.PE2012
An experimental test for genetic constraints in Drosophila melanogaster
Ian Dworkin, David Tack, Jarrod Hadfield
In addition to natural selection, adaptive evolution requires genetic variation to proceed. Yet the G-matrix may have limited 'genetic degrees of freedom', with certain combination…