3 papers
q-bio.BM2026
SeedProteo: Accurate De Novo All-Atom Design of Protein Binders
Wei Qu, Yiming Ma, Fei Ye +6
We present SeedProteo, a diffusion-based model for de novo all-atom protein design. We demonstrate how to repurpose a cutting-edge folding architecture into a powerful generative d…
cs.LG2025
Elucidating the Design Space of Multimodal Protein Language Models
Cheng-Yen Hsieh, Xinyou Wang, Daiheng Zhang +5
Multimodal protein language models (PLMs) integrate sequence and token-based structural information, serving as a powerful foundation for protein modeling, generation, and design.…
q-bio.BM2024
ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone Design
Yiming Ma, Fei Ye, Yi Zhou +3
Nature creates diverse proteins through a 'divide and assembly' strategy. Inspired by this idea, we introduce ProteinWeaver, a two-stage framework for protein backbone design. Our…