66 citations · 200 across the 6 of their papers we have counts for
6 papers
Multiplexing oscillatory biochemical signals
Wiet de Ronde, Pieter Rein ten Wolde
In recent years it is increasingly being recognized that biochemical signals are not necessarily constant in time and that the temporal dynamics of a signal can be the information…
Protein logic: a statistical mechanical study of signal integration at the single-molecule level
Wiet de Ronde, Pieter Rein ten Wolde, Andrew Mugler
Information processing and decision making is based upon logic operations, which in cellular networks has been well characterized at the level of transcription. In recent years how…
Reliability of frequency- and amplitude-decoding in gene regulation
Filipe Tostevin, Wiet de Ronde, Pieter Rein ten Wolde
In biochemical signaling, information is often encoded in oscillatory signals. However, the advantages of such a coding strategy over an amplitude encoding scheme of constant signa…
Multiplexing Biochemical Signals
Wiet de Ronde, Filipe Tostevin, Pieter Rein ten Wolde
In this paper we show that living cells can multiplex biochemical signals, i.e. transmit multiple signals through the same signaling pathway simultaneously, and yet respond to them…
The effect of feedback on the fidelity of information transmission of time-varying signals
Wiet de Ronde, Filipe Tostevin, Pieter Rein ten Wolde
Living cells are continually exposed to environmental signals that vary in time. These signals are detected and processed by biochemical networks, which are often highly stochastic…
Statistical properties of multistep enzyme-mediated reactions
Wiet H. de Ronde, Bryan C. Daniels, Andrew Mugler +2
Enzyme-mediated reactions may proceed through multiple intermediate conformational states before creating a final product molecule, and one often wishes to identify such intermedia…