571 citations · 1.6k across the 14 of their papers we have counts for
14 papers
Genetic similarity versus genetic ancestry groups as sample descriptors in human genetics
Graham Coop
A common sample descriptor in human genomics studies is that of 'genetic ancestry group', with terms such as 'European genetic ancestry' or 'East Asian genetic ancestry' frequently…
Reading tea leaves? Polygenic scores and differences in traits among groups
Graham Coop
In the past decade, Genome-Wide Association Studies (GWAS) have delivered an increasingly broad view of the genetic basis of human phenotypic variation. One of the major developmen…
Demographic inference for spatially heterogeneous populations using long shared haplotypes
Raphael Forien, Harald Ringbauer, Graham Coop
We introduce a modified spatial -Fleming-Viot process to model the ancestry of individuals in a population occupying a continuous spatial habitat divided into two areas by a sha…
A genomic map of the effects of linked selection in Drosophila
Eyal Elyashiv, Shmuel Sattath, Tina T. Hu +5
Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of 'linked selection' on levels of genetic diversity is key to making re…
Speciation and introgression between Mimulus nasutus and Mimulus guttatus
Yaniv Brandvain, Amanda M. Kenney, Lex Flagel +2
Mimulus guttatus and M. nasutus are an evolutionary and ecological model sister species pair differentiated by ecology, mating system, and partial reproductive isolation. Despite e…
Genomic identification of founding haplotypes reveals the history of the selfing species Capsella rubella
Yaniv Brandvain, Tanja Slotte, Khaled Hazzouri +2
The shift from outcrossing to self-fertilization is among the most common transitions in plants. Until recently, however, a genome-wide view of this transition has been obscured by…
The Population Genetic Signature of Polygenic Local Adaptation
Jeremy J. Berg, Graham Coop
Adaptation in response to selection on polygenic phenotypes may occur via subtle allele frequencies shifts at many loci. Current population genomic techniques are not well posed to…
Disentangling the effects of geographic and ecological isolation on genetic differentiation
Gideon Bradburd, Peter Ralph, Graham Coop
Populations can be genetically isolated both by geographic distance and by differences in their ecology or environment that decrease the rate of successful migration. Empirical stu…
Robust identification of local adaptation from allele frequencies
Torsten Günther, Graham Coop
Comparing allele frequencies among populations that differ in environment has long been a tool for detecting loci involved in local adaptation. However, such analyses are complicat…
The geography of recent genetic ancestry across Europe
Peter Ralph, Graham Coop
The recent genealogical history of human populations is a complex mosaic formed by individual migration, large-scale population movements, and other demographic events. Population…
Patterns of neutral diversity under general models of selective sweeps
Graham Coop, Peter Ralph
Two major sources of stochasticity in the dynamics of neutral alleles result from resampling of finite populations (genetic drift) and the random genetic background of nearby selec…
Is your phylogeny informative? Measuring the power of comparative methods
Carl Boettiger, Graham Coop, Peter Ralph
Phylogenetic comparative methods may fail to produce meaningful results when either the underlying model is inappropriate or the data contain insufficient information to inform the…
Scrambling eggs: Meiotic drive and the evolution of female recombination rates
Yaniv Brandvain, Graham Coop
Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of s…
Parallel adaptation: One or many waves of advance of an advantageous allele?
Peter Ralph, Graham Coop
Our models for detecting the effect of adaptation on population genomic diversity are often predicated on a single newly arisen mutation sweeping rapidly to fixation. However, a po…