2 papers
stat.AP2026
VAE-MS: An Asymmetric Variational Autoencoder for Mutational Signature Extraction
Ida Egendal, Rasmus Froberg Brøndum, Dan J Woodcock +2
Mutational signature analysis has emerged as a powerful method for uncovering the underlying biological processes driving cancer development. However, the signature extraction proc…
stat.AP2024
On the Relation Between Autoencoders and Non-negative Matrix Factorization, and Their Application for Mutational Signature Extraction
Ida Egendal, Rasmus Froberg Brøndum, Marta Pelizzola +2
The aim of this study is to provide a foundation to understand the relationship between non-negative matrix factorization (NMF) and non-negative autoencoders enabling proper interp…