activity
20122020
most citedDistant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein: a potential hint at the possibility of local iron dysregulation in COVID-19

89 citations · 110 across the 8 of their papers we have counts for

collaborators

8 papers

q-bio.BM2020★ 89 cited

Distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein: a potential hint at the possibility of local iron dysregulation in COVID-19

Sepehr Ehsani

The spike glycoprotein of the SARS-CoV-2 virus, which causes COVID-19, has attracted attention for its vaccine potential and binding capacity to host cell surface receptors. Much o…

q-bio.OT2019★ 2 cited

The challenges of purely mechanistic models in biology and the minimum need for a 'mechanism-plus-X' framework

Sepehr Ehsani

Ever since the advent of molecular biology in the 1970s, mechanical models have become the dogma in the field, where a "true" understanding of any subject is equated to a mechanist…

q-bio.OT2016★ 5 cited

A framework for philosophical biology

Sepehr Ehsani

Advances in biology have mostly relied on theories that were subsequently revised, expanded or eventually refuted using experimental and other means. Theoretical biology used to pr…

q-bio.QM2015

Identification of the Zeo1 Protein as a Candidate Structural Homolog of α-Synuclein in Budding Yeast

Sepehr Ehsani

Human α-synuclein (SNCA) is a 140-amino-acid protein belonging to the three-member synuclein family. It has been extensively studied due to its misfolding/aggregation in and geneti…

q-bio.QM2013★ 3 cited

Correlative-causative structures and the 'pericause': an analysis of causation and a model based on cellular biology

Sepehr Ehsani

The advent of molecular biology has led to the identification of definitive causative factors for a number of diseases, most of which are monogenic. Causes for most common diseases…

q-bio.QM2013★ 4 cited

Macro-trends in research on the central dogma of molecular biology

Sepehr Ehsani

The central dogma of molecular biology, formulated more than five decades ago, compartmentalized information exchange in the cell into the DNA, RNA and protein domains. This formal…