142 citations · 523 across the 30 of their papers we have counts for
43 papers
Complete characterization of robust perfect adaptation in biochemical reaction networks
Yuji Hirono, Ankit Gupta, Mustafa Khammash
Perfect adaptation is a phenomenon whereby the output variables of a system can maintain certain values despite external disturbances. Robust perfect adaptation (RPA) refers to an…
Noise in Biomolecular Systems: Modeling, Analysis, and Control Implications
Corentin Briat, Mustafa Khammash
While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncert…
Structural Stability Properties of Antithetic Integral (Rein) Control with Output Inhibition
Corentin Briat, Mustafa Khammash
Perfect adaptation is a well-studied biochemical homeostatic behavior lying at the core of biochemical regulation. While the concepts of homeostasis and perfect adaptation are not…
Design of a synthetic integral feedback circuit: dynamic analysis and DNA implementation
Corentin Briat, Christoph Zechner, Mustafa Khammash
The design and implementation of regulation motifs ensuring robust perfect adaptation are challenging problems in synthetic biology. Indeed, the design of high-yield robust metabol…
Optimal and Control of Stochastic Reaction Networks
Corentin Briat, Mustafa Khammash
Stochastic reaction networks is a powerful class of models for the representation a wide variety of population models including biochemistry. The control of such networks has been…
Convergence of regularized particle filters for stochastic reaction networks
Zhou Fang, Ankit Gupta, Mustafa Khammash
Filtering for stochastic reaction networks (SRNs) is an important problem in systems/synthetic biology aiming to estimate the state of unobserved chemical species. A good solution…