3 papers
physics.bio-ph2026
Local stabilizability implies global controllability in catalytic reaction systems
Yusuke Himeoka, Shuhei A. Horiguchi, Naoto Shiraishi +2
Controlling complex reaction networks is a fundamental challenge in the fields of physics, biology, and systems engineering. Here, we prove a general principle for catalytic reacti…
q-bio.PE2025
Optimal control of stochastic reaction networks with entropic control cost and emergence of mode-switching strategies
Shuhei A. Horiguchi, Tetsuya J. Kobayashi
Controlling the stochastic dynamics of biological populations is a challenge that arises across various biological contexts. However, these dynamics are inherently nonlinear and in…
physics.bio-ph2024
A theoretical basis for cell deaths
Yusuke Himeoka, Shuhei A. Horiguchi, Tetsuya J. Kobayashi
Understanding deaths and life-death boundaries of cells is a fundamental challenge in biological sciences. In this study, we present a theoretical framework for investigating cell…