4 papers
Making Models That Matter: How to Build Trustworthy and Useful Systems Biology Models
John M. Hancock, Mihail Anton, Frank T. Bergmann +23
Computational models supporting mechanistic understanding of (complex) biological systems, systems behaviour prediction, and experimental design are becoming more and more embedded…
Patterns of positive selection in seven ant genomes
Julien Roux, Eyal Privman, Sebastien Moretti +3
The evolution of ants is marked by remarkable adaptations that allowed the development of very complex social systems. To identify how ant-specific adaptations are associated with…
The hourglass and the early conservation models - co-existing evolutionary patterns in vertebrate development
Barbara Piasecka, Pawel Lichocki, Sebastien Moretti +2
Developmental constraints have been postulated to limit the space of feasible phenotypes and thus shape animal evolution. These constraints have been suggested to be the strongest…
gcodeml: A Grid-enabled Tool for Detecting Positive Selection in Biological Evolution
Sébastien Moretti, Riccardo Murri, Sergio Maffioletti +5
One of the important questions in biological evolution is to know if certain changes along protein coding genes have contributed to the adaptation of species. This problem is known…