271 citations · 402 across the 8 of their papers we have counts for
9 papers
microRNA-mediated noise processing in cells: a fight or a game?
Elsi Ferro, Chiara Enrico Bena, Silvia Grigolon +1
In the past decades microRNAs (miRNA) have much attracted the attention of researchers at the interface between life and theoretical sciences for their involvement in post-transcri…
Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs
Araks Martirosyan, Marco Del Giudice, Chiara Enrico Bena +3
Non-conding RNAs play a key role in the post-transcriptional regulation of mRNA translation and turnover in eukaryotes. miRNAs, in particular, interact with their target RNAs throu…
Initial cell density encodes proliferative potential in cancer cell populations
Chiara Enrico Bena, Marco Del Giudice, Alice Grob +8
Individual cells exhibit specific proliferative responses to changes in microenvironmental conditions. Whether such potential is constrained by the cell density throughout the grow…
On the role of extrinsic noise in microRNA-mediated bimodal gene expression
Marco Del Giudice, Stefano Bo, Silvia Grigolon +1
Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Experimental evidences of phenotypic differe…
Quantitative study of crossregulation, noise and synchronization between microRNA targets in single cells
Carla Bosia, Francesco Sgrò, Laura Conti +6
Recent studies reported complex post-transcriptional interplay among targets of a common pool of microRNAs, a class of small non-coding downregulators of gene expression. Behaving…
A combination of transcriptional and microRNA regulation improves the stability of the relative concentrations of target genes
Andrea Riba, Carla Bosia, Mariama El Baroudi +2
It is well known that, under suitable conditions, microRNAs are able to fine tune the relative concentration of their targets to any desired value. We show that this function is pa…
Modeling competing endogenous RNAs networks
Carla Bosia, Andrea Pagnani, Riccardo Zecchina
MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs). They accomplish key roles in gene r…
Gene autoregulation via intronic microRNAs and its functions
Carla Bosia, Matteo Osella, Mariama El Baroudi +2
Background: MicroRNAs, post-transcriptional repressors of gene expression, play a pivotal role in gene regulatory networks. They are involved in core cellular processes and their d…
The role of incoherent microRNA-mediated feedforward loops in noise buffering
Matteo Osella, Carla Bosia, Davide Cora' +1
MicroRNAs are endogenous non-coding RNAs which negatively regulate the expression of protein-coding genes in plants and animals. They are known to play an important role in several…