2 citations · 7 across the 5 of their papers we have counts for
5 papers
On separation of time scales in pharmacokinetics
S. Piekarski, M. Rewekant
A lot of criticism against the standard formulation of pharmacokinetics has been raised by several authors. It seems that the natural reaction for that criticism is to comment it f…
On the Way to More Convenient Description of Drug-Plasma Protein Binding
Piekarski S., M. Rewekant
The theoretical case is considered where the total amount of plasma protein is conserved, but the drug is eliminated after its single application. After a single drug application a…
On applications of conservation laws in pharmacokinetics
S. Piekarski, M. Rewekant
There has been certain criticism raised by A. Rescigno [2,8,9,12-15] against the standard formulation of pharmacokinetics. In 2011 it has been suggested that inconsistencies in pha…
On inconsistencies in passive pharmacokinetics
Slawomir Piekarski, Miroslaw Rewekant
Some inconsistencies in the passive pharmacokinetics has been observed many years ago. It is possible these inconsistencies result from the lack of proper evolution equations. In t…
On drug transport after intravenous administration
Slawomir Piekarski, Miroslaw Rewekant
A mathematical model of a drug transport after rapid injection is given. It takes into account three processes: - drug plasma protein binding in central compartment - transport pro…