978 citations · 1.1k across the 7 of their papers we have counts for
Showing 2014Show all
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q-bio.PE2014★ 1 cited
The impact of macroscopic epistasis on long-term evolutionary dynamics
Benjamin H. Good, Michael M. Desai
Genetic interactions can strongly influence the fitness effects of individual mutations, yet the impact of these epistatic interactions on evolutionary dynamics remains poorly unde…
q-bio.PE2014★ 1 cited
Deleterious passengers in adapting populations
Benjamin H Good, Michael M Desai
Most new mutations are deleterious and are eventually eliminated by natural selection. But in an adapting population, the rapid amplification of beneficial mutations can hinder the…
q-bio.PE2014★ 69 cited
The Fates of Mutant Lineages and the Distribution of Fitness Effects of Beneficial Mutations in Laboratory Budding Yeast Populations
Evgeni M. Frenkel, Benjamin H. Good, Michael M. Desai
The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting microbial populations, this process is particularly hard to predict because lineages…