13 citations · 14 across the 4 of their papers we have counts for
4 papers
Automated deconvolution of structured mixtures from bulk tumor genomic data
Theodore Roman, Lu Xie, Russell Schwartz
Motivation: As cancer researchers have come to appreciate the importance of intratumor heterogeneity, much attention has focused on the challenges of accurately profiling heterogen…
Derivative-free optimization of rate parameters of capsid assembly models from bulk in vitro data
Lu Xie, Gregory R. Smith, Russell Schwartz
The assembly of virus capsids from free coat proteins proceeds by a complicated cascade of association and dissociation steps, the great majority of which cannot be directly experi…
Avoid Internal Loops in Steady State Flux Space Sampling
Lu Xie
As a widely used method in metabolic network studies, Monte-Carlo sampling in the steady state flux space is known for its flexibility and convenience of carrying out different pur…
Imposition of Different Optimizing Object with Non-Linear Constraints on Flux Sampling and Elimination of Free Futile Pathways
Lu Xie, Yi Zhang
Constraint-based modeling has been widely used on metabolic networks analysis, such as biosynthetic prediction and flux optimization. The linear constraints, like mass conservation…