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q-bio.BM2023★ 16 cited
Predicting a Protein's Stability under a Million Mutations
Jeffrey Ouyang-Zhang, Daniel J. Diaz, Adam R. Klivans +1
Stabilizing proteins is a foundational step in protein engineering. However, the evolutionary pressure of all extant proteins makes identifying the scarce number of mutations that…
cs.CV2023
Long-tail Detection with Effective Class-Margins
Jang Hyun Cho, Philipp Krähenbühl
Large-scale object detection and instance segmentation face a severe data imbalance. The finer-grained object classes become, the less frequent they appear in our datasets. However…