3.1k citations · 4.7k across the 6 of their papers we have counts for
6 papers
Joint analysis of functional genomic data and genome-wide association studies of 18 human traits
Joseph K. Pickrell
Annotations of gene structures and regulatory elements can inform genome-wide association studies (GWAS). However, choosing the relevant annotations for interpreting an association…
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
Bogdan Pasaniuc, Noah Zaitlen, Huwenbo Shi +7
Imputation using external reference panels is a widely used approach for increasing power in GWAS and meta-analysis. Existing HMM-based imputation approaches require individual-lev…
Ancient west Eurasian ancestry in southern and eastern Africa
Joseph K. Pickrell, Nick Patterson, Po-Ru Loh +5
The history of southern Africa involved interactions between indigenous hunter-gatherers and a range of populations that moved into the region. Here we use genome-wide genetic data…
Inferring Admixture Histories of Human Populations Using Linkage Disequilibrium
Po-Ru Loh, Mark Lipson, Nick Patterson +4
Long-range migrations and the resulting admixtures between populations have been important forces shaping human genetic diversity. Most existing methods for detecting and reconstru…
The genetic prehistory of southern Africa
Joseph K. Pickrell, Nick Patterson, Chiara Barbieri +18
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their re…
Inference of population splits and mixtures from genome-wide allele frequency data
Joseph K. Pickrell, Jonathan K. Pritchard
Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a cha…