14 citations · 31 across the 8 of their papers we have counts for
8 papers
Stochastics of DNA Quantification
Abdoelnaser M Degoot, Wilfred Ndifon
A common approach to quantifying DNA involves repeated cycles of DNA amplification. This approach, employed by the polymerase chain reaction (PCR), produces outputs that are corrup…
A strategy for finding people infected with SARS-CoV-2: optimizing pooled testing at low prevalence
Leon Mutesa, Pacifique Ndishimye, Yvan Butera +18
Suppressing SARS-CoV-2 will likely require the rapid identification and isolation of infected individuals, on an ongoing basis. RT-PCR (reverse transcription polymerase chain react…
Trans-allelic model for prediction of peptide:MHC-II interactions
A. M. Degoot, Faraimunashe Chirove, Wilfred Ndifon
Major histocompatibility complex class two (MHC-II) molecules are trans-membrane proteins and key components of the cellular immune system. Upon recognition of foreign peptides exp…
Dynamic regulation of T cell activation by coupled feedforward loops
Gershom Buri, Girma Mesfin Zelleke, Wilfred Ndifon
The adaptive immune system responds to foreign invaders by activating T cells. However, this response is perilous if T cells are activated by the wrong signal or if they remain act…
A contact-waiting-time metric and RNA folding rates
Asamoah Nkwanta, Wilfred Ndifon
Metrics for indirectly predicting the folding rates of RNA sequences are of interest. In this letter, we introduce a simple metric of RNA structural complexity, which accounts for…
On the accessibility of adaptive phenotypes of a bacterial metabolic network
Wilfred Ndifon, Joshua B. Plotkin, Jonathan Dushoff
The mechanisms by which adaptive phenotypes spread within an evolving population after their emergence are understood fairly well. Much less is known about the factors that influen…