98 citations · 100 across the 4 of their papers we have counts for
4 papers
Using Simulations and kinetic network models to reveal the dynamics and functions of Riboswitches
Jong-Chin Lin, Jeseong Yoon, Changbong Hyeon +1
Riboswitches, RNA elements found in the untranslated region, regulate gene expression by binding to target metaboloites with exquisite specificity. Binding of metabolites to the co…
Dynamical Transition and Heterogeneous Hydration Dynamics in RNA
Jeseong Yoon, Jong-Chin Lin, Changbong Hyeon +1
Enhanced dynamical fluctuations of RNAs, facilitated by a network of water molecules with strong interactions with RNA, are suspected to be critical in their ability to respond to…
Urea-induced denaturation of PreQ1-riboswitch
Jeseong Yoon, D. Thirumalai, Changbong Hyeon
Urea, a polar molecule with a large dipole moment, not only destabilizes the folded RNA structures, but can also enhance the folding rates of large ribozymes. Unlike the mechanism…
Hidden Complexity in the Isomerization Dynamics of Holliday Junctions
Changbong Hyeon, Jinwoo Lee, Jeseong Yoon +2
A plausible consequence of rugged energy landscapes of biomolecules is that functionally competent folded states may not be unique, as is generally assumed. Indeed, molecule-to-mol…