43 citations · 48 across the 8 of their papers we have counts for
4 papers · 1 filter
Topological spectra and entropy of chromatin loop networks
Andrea Bonato, Dom Corbett, Sergey Kitaev +3
The 3D folding of a mammalian gene can be studied by a polymer model, where the chromatin fibre is represented by a semiflexible polymer which interacts with multivalent proteins,…
Combinatorics and topological weights of chromatin loop networks
Andrea Bonato, Dom Corbett, Sergey Kitaev +3
Polymer physics models suggest that chromatin spontaneously folds into loop networks with transcription units (TUs), such as enhancers and promoters, as anchors. Here we use combin…
Extrusion without a motor: a new take on the loop extrusion model of genome organization
C. A. Brackley, J. Johnson, D. Michieletto +4
Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangeme…
A 1-dimensional statistical mechanics model for nucleosome positioning on genomic DNA
S. Tesoro, I. Ali, A. N. Morozov +2
The first level of folding of DNA in eukaryotes is provided by the so called '10 nm chromatin fibre', where DNA wraps around histone proteins (approx. 10 nm in size) to form nucleo…