Advancing Evidence Generation in Biomedical Research Using Natural Hermite and Propensity Score Indices: Applications to External Control Arms

Javier Cabrera, Berhanu Alemayehu, Demissie Alemayehu +1

When it is not feasible to conduct randomized controlled trials (RCTs), the use of external control arms based on real-world data (RWD) may be a viable option. However, challenges…