21 citations · 57 across the 5 of their papers we have counts for
5 papers
Using Simulations and kinetic network models to reveal the dynamics and functions of Riboswitches
Jong-Chin Lin, Jeseong Yoon, Changbong Hyeon +1
Riboswitches, RNA elements found in the untranslated region, regulate gene expression by binding to target metaboloites with exquisite specificity. Binding of metabolites to the co…
Dynamical Transition and Heterogeneous Hydration Dynamics in RNA
Jeseong Yoon, Jong-Chin Lin, Changbong Hyeon +1
Enhanced dynamical fluctuations of RNAs, facilitated by a network of water molecules with strong interactions with RNA, are suspected to be critical in their ability to respond to…
Sequence-dependent folding landscapes of adenine riboswitch aptamers
Jong-Chin Lin, Changbong Hyeon, D. Thirumalai
Prediction of the functions of riboswitches requires a quantitative description of the folding landscape so that the barriers and time scales for the conformational change in the s…
RNA under Tension: Folding Landscapes, Kinetic Partitioning Mechanism, and Molecular Tensegrity
Jong-Chin Lin, Changbong Hyeon, D. Thirumalai
Non-coding RNA sequences play a great role in controlling a number of cellular functions, thus raising the need to understand their complex conformational dynamics in quantitative…
Gene Regulation by Riboswitches with and without Negative Feedback Loop
Jong-Chin Lin, D. Thirumalai
Riboswitches, structured elements in the untranslated regions of messenger RNAs, regulate gene expression by binding specific metabolites. We introduce a kinetic network model that…