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Genome-wide scan of 29,141 African Americans finds no evidence of selection since admixture
Gaurav Bhatia, Arti Tandon, Melinda C. Aldrich +44
We scanned through the genomes of 29,141 African Americans, searching for loci where the average proportion of African ancestry deviates significantly from the genome-wide average.…
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis, Nick Patterson, Alissa Mittnik +117
We sequenced genomes from a 7,000 year old early farmer from Stuttgart in Germany, an 8,000 year old hunter-gatherer from Luxembourg, and seven 8,000 year old hun…
Response to a population bottleneck can be used to infer recessive selection
Daniel J. Balick, Ron Do, David Reich +1
Here we present the first genome wide statistical test for recessive selection. This test uses explicitly non-equilibrium demographic differences between populations to infer the m…
Ancient west Eurasian ancestry in southern and eastern Africa
Joseph K. Pickrell, Nick Patterson, Po-Ru Loh +5
The history of southern Africa involved interactions between indigenous hunter-gatherers and a range of populations that moved into the region. Here we use genome-wide genetic data…